• Before and after 8 weeks face comparison of a woman with freckles, with a Pigment Restraint Cream jar and benefit icons
  • Smiling woman in a white shirt beside skin type swatches and icons, headed Effective Skin Protection
  • Smiling woman applying a dab of cream to her cheek with the headline Hydrates, Balances and Revives Skin
  • Before and after side-profile photos of a woman's face with a Pigment Restraint Cream 2 jar and four benefit icons
  • SPF 50+ bottle with a tinted cream swatch beside photos of where to apply it: face, neck, hands, body, elbows, feet
  • Mesoderm RX Hydrating Skin Booster bottle beside four skin benefit icons
  • Pigment Restraint SPF 50+ bottle on a round stand surrounded by six formula benefit callouts
  • Mesoderm RX Pigment Restraint Cream 2 jar with silver lid in front of its white box
  • Hands holding a Mesoderm RX Collagen Revitalizer bottle beside three self-assessment study percentages
  • Before and after 8 weeks side-profile comparison of a woman's face with a Pigment Restraint Cream jar and benefit icons
  • Before and after 8 weeks face comparison of a woman in a white headband, with a Pigment Restraint Cream jar
  • Woman with eyes closed opening a jar of Mesoderm RX Pigment Restraint Cream 2
  • SPF 50+ tinted emulsion bottle beside three ingredient groups shown as powder and serum textures
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4.9/5 across 1,236 customers

Complete Radiance Trio

Complete Radiance Trio

Three Targeted Formulas. One Complete Facial Care Routine.

$99.99
$199.99 $99.99
Save $100.00
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Free US shipping on orders over $59

  • 60-Day Money-Back Guarantee
  • Secure checkout
  • Cruelty-Free, Formulated in the USA

 What it does

  •  Hydrates and visibly plumps skin 
  •  Supports a more even-looking tone 
  •  Helps improve the look of dark spots 
  •  Provides broad-spectrum SPF 50+ protection 
How it works

Benefits

Beautiful Skin Starts With Consistent Care

1. BRIGHTER-LOOKING COMPLEXION

Helps improve the appearance of uneven skin tone, visible dark spots, and post-blemish marks.

2. DEEP HYDRATION

Replenishes moisture to leave skin feeling softer, smoother, and more comfortable.

3. SMOOTHER-LOOKING TEXTURE

Supports a visibly refined complexion and helps reduce the appearance of dryness-related fine lines.

4. DAILY SUN PROTECTION

Broad-spectrum SPF 50+ helps protect against UVA and UVB rays, an essential part of caring for skin prone to sun-induced discoloration.

5. COMPLETE FACIAL CARE

Three complementary formulas designed to work within a simple morning and nighttime skincare routine.

How to use

Daily on clean skin, massaged until absorbed

Morning hydration, daytime protection, nighttime brightening.

MORNING ROUTINE

  • CLEANSE your face gently and pat dry.
  • HYDRATE with 2–3 pumps of Hydrating Skin Booster. Smooth over the face and neck, avoiding the eye area.
  • PROTECT with Pigment Restraint Ultra High Sun Protection SPF 50+. Apply generously as the final morning skincare step.
  • REAPPLY SPF at least every 2 hours while exposed to sunlight, following the product label.

NIGHTTIME ROUTINE

  • CLEANSE your face thoroughly and pat dry.
  • APPLY a thin, even layer of Pigment Restraint Cream to the face, avoiding the eyes and lips.
  • ALLOW TO ABSORB completely. Do not rinse.
  • USE NIGHTLY as directed.

For external use only. Discontinue use if irritation occurs. Follow the individual product labels for additional precautions.

Ingredients

Kojic Acid, Alpha Arbutin, Azelaic Acid, Hyaluronic Acid, Peptides, UV Filters

Three Complementary Formulas. Thoughtfully Selected Ingredients.

PIGMENT RESTRAINT CREAM — Brightening Care

  • Kojic Acid: Helps improve the appearance of dark spots and uneven tone.
  • Alpha Arbutin: Supports a brighter, more even-looking complexion.
  • Azelaic Acid: Helps refine the appearance of skin texture and visible discoloration.
  • Phytic Acid: Provides antioxidant care for dull-looking skin.

HYDRATING SKIN BOOSTER — Moisture & Radiance

  • Hyaluronic Acid: Attracts moisture to help skin feel hydrated and plump.
  • Peptides: Support the appearance of smoother, firmer-looking skin.
  • Bisabolol: A skin-conditioning ingredient that supports comfort and softness.

SPF 50+ SUN PROTECTION — Daily Defense

  • UV Filters: Formulated to provide broad-spectrum sun protection.
  • Glycerin: Helps maintain skin hydration.
  • Bisabolol: Provides skin-conditioning benefits.
  • Tinted Formula: Complements the appearance of the skin while providing daily sunscreen coverage.

Each product features its own formula designed for a specific step in your daily skincare routine.

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Free US shipping over $59 · 60-Day Money-Back Guarantee
  • Free standard US shipping on orders over $59 (3 to 5 business days). 
  • Orders ship within 1 to 2 business days; orders after 2 PM ET ship the next business day.
  • 60-day money-back guarantee on unused, unopened items.
  • Damaged or wrong item? Contact us within 7 days and we will replace or refund it.

Shipping policy · Return policy

  • Fragrance free
  • No added alcohol
  • Sensitive-skin tested
  • Vegan
  • Certified clean
  • Climate neutral
  • Plastic neutral
View full details

THREE ESSENTIALS. ONE COMPLETE FACIAL CARE ROUTINE.

Your Glow Starts With the Right Routine.

Beautiful-looking skin takes more than one step. It takes a thoughtful balance of targeted care, daily moisture, and sun protection.

The Mesoderm RX Complete Radiance Trio brings together three complementary formulas for a simple, effective-feeling skincare experience.

Pigment Restraint Cream provides nighttime care to help improve the appearance of dark spots and uneven tone.

Hydrating Skin Booster delivers lightweight hydration to support a softer, smoother, plumper-looking complexion.

SPF 50+ Sun Protection helps defend against daily UVA/UVB exposure, completing your morning routine.

Brighten at night. Hydrate and protect by day.

  1. 1Pigment cells make melanin and pass it up to the surface.
  2. 2Brightening actives help interrupt that hand-off.
  3. 3Less pigment reaches the surface, so tone looks more even.

NIGHT CARE

Brightening ingredients that help the look of dark spots fade over time.

Before
After

Customer photos. Individual results vary.

How to use

Your Complete Body Brightening Routine

  1. Apply Advanced Body Essence Lotion

    Massage a generous amount onto your arms, legs, knees, elbows, and other desired body areas until fully absorbed. Use daily.

  2. Apply Intimate Brightening Cream

    Apply a thin layer to clean, dry external areas such as the underarms, bikini line, or inner thighs. Gently massage until absorbed. Use twice daily as directed.

  3. Stay Consistent

    Incorporate both formulas into your regular body care routine. Consistent application helps support the appearance of smoother, more even-looking skin.

Pigment Restraint Cream

Target Dark Spots. Reveal Your Radiance. 

Give your nighttime skincare routine a more focused approach with Mesoderm RX Pigment Restraint Cream.

This brightening facial cream helps improve the appearance of visible dark spots, post-blemish marks, and uneven skin tone while supporting a smoother, more radiant-looking complexion.

Your nighttime essential for beautifully even-looking skin.

Hydrating Skin Booster

Your Daily Dose of Hydration. 

Refresh your complexion with Mesoderm RX Hydrating Skin Booster, a lightweight formula designed to replenish moisture and support softer, smoother-looking skin.

Featuring hyaluronic acid and peptides, this daily hydrating essential helps improve the appearance of dryness-related fine lines while leaving skin feeling supple and comfortably moisturized.

Hydrated skin. A fresh glow. Everyday confidence.

SPF 50+ Sun Protection

 Protect Your Glow Every Day. 

Complete your morning routine with Mesoderm RX Pigment Restraint Ultra High Sun Protection SPF 50+.

This lightweight tinted sunscreen provides broad-spectrum UVA/UVB protection while helping maintain the appearance of a more even-looking complexion.

Designed for daily wear, it complements your skincare routine with essential sun protection and a comfortable finish.

Because protecting your skin is part of keeping it beautiful.

What to expect

  1. Weeks 1–2

    Hydration & Comfort

    Skin feels softer, smoother, and more moisturized with regular use.

  2. Weeks 3–4

    Improved Appearance

    With continued application, skin may begin to look fresher and more even-toned.

  3. Weeks 6–8

    Long-Term Body Care

    Consistent use helps maintain the appearance of hydrated, radiant, well-cared-for skin.

Timelines reflect typical customer feedback with consistent use. Individual results vary.

Your Morning & Nighttime Body Care Routine

Two targeted formulas for daily body care, with an optional third step to complete your routine. — Additional Products Sold Separately.

Morning routine

Hydrate, even the look of dark spots, protect from UV.

Total $98.97 Ships free

New to acids or retinoids? Start every other night and patch test first.

What customers say

Real results, real customers

reported long-lasting hydration and nourishment
95%
experienced smoother texture and clearer complexion
93%
saw reduced fine lines and smoother skin
92%
noticed enhanced skin elasticity and firmness
88%

Based on a study of 100 participants. Individual results vary.

Before
After
Before
After
Before
After
Before
After

Try it for 60 days

If it is not right for you, return unused, unopened items within 60 days of delivery for a refund. Read the policy

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Questions, answered

Ask us anything
What is included in the Complete Radiance Trio?

The trio includes one Pigment Restraint Cream, one Hydrating Skin Booster, and one Pigment Restraint Ultra High Sun Protection SPF 50+.

Can I use all three products every day?

Yes, following their individual directions. Use Hydrating Skin Booster in the morning, SPF 50+ as your final morning skincare step, and Pigment Restraint Cream as part of your nighttime routine.

Should Pigment Restraint Cream be applied in the morning or at night?

The recommended routine for this collection places Pigment Restraint Cream at night. Follow the approved product label for frequency and application instructions.

How often should I use Hydrating Skin Booster?

Use once daily on clean skin, applying 2–3 pumps over the face and neck while avoiding the eye area.

Is sunscreen necessary when using Pigment Restraint Cream?

Daily sunscreen is an important part of caring for skin prone to visible sun-related dark spots. Apply SPF 50+ in the morning and reapply as directed.

Can Hydrating Skin Booster be used under sunscreen?

Yes. Apply the lightweight booster first, allow it to absorb, and follow with your SPF 50+ sunscreen.

Is the sunscreen tinted?

Yes. Pigment Restraint Ultra High Sun Protection is described as a tinted sunscreen on its individual product page.

Can I use the trio with other skincare products?

The trio can be incorporated into a broader skincare routine. Introduce additional active ingredients carefully and follow the directions for each product.

How long will it take to see results?

Results vary depending on individual skin characteristics and consistent use. Hydration may be noticeable sooner, while changes in the appearance of uneven skin tone may take longer.

How fast is shipping?

Orders ship within 1 to 2 business days. Standard US shipping takes 3 to 5 business days and is free on orders over $59. 

What if it is not right for me?

Unused, unopened items can be returned within 60 days of delivery under our money-back guarantee. If an item arrives damaged or incorrect, contact us within 7 days and we will replace or refund it. Read the full policy.

How do subscriptions work?

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