Rated 4.9/5 across 1,236 customers
Even, brighter-looking skin. Face to body.
Hydroquinone-free brightening for face and body, Made in the USA.
- 60-Day Money-Back Guarantee
- Cruelty-Free, Made in the USA
As seen in
Shop by concern
Shop all
Dark spots and dullness
Our solution
AHA + BHA + PHA Serum
$29.99
Stubborn spots and sun marks
Our solution
Pigment Restraint Cream
$49.99
Underarms and bikini line
Our solution
Intimate Brightening Cream
$40.99
Daily sun protection
Our solution
Pigment Restraint SPF 50+
$29.99
Uneven tone on the body
Our solution
Advanced BodyEssence Lotion
$27.99
Fine lines and firmness
Our solution
Age-Defying Serum
$34.95
What sets us apart
Skincare built around how pigment actually forms.
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Several actives, one formula
The serum pairs three acids; the intimate cream, five brighteners. One job each.
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Brightening without hydroquinone
Every formula is hydroquinone free, so it suits daily, long-term use.
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Made to layer
Morning and night routines designed to go together, from exfoliation to SPF.
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A 60-Day Guarantee
Return unused, unopened items within 60 days of delivery.
Brighter skin is a routine, not one product
Three steps in the morning, three at night, added to your cart in one tap.
Morning routine
Hydrate, brighten, then protect from UV.
Total $119.97 Ships free
Night routine
Renew, treat fine lines, nourish while you sleep.
Total $94.93 Ships free
Why a routine works
- Each step has one job.Exfoliate, treat, hydrate and protect without doubling up.
- Morning protects, night renews.Daily SPF guards the progress your night routine makes.
- Free US shipping, built in.Every full routine clears our $59 free-shipping threshold.
New to acids or retinoids? Start every other night and patch test first.
Real routines, real results
Our values, in every bottle
For over two decades, we have made skincare we would use ourselves.
- Clean by defaultParaben free and sulfate free.
- Kind to sensitive skinDye free and fragrance free.
- Cruelty-freeLeaping Bunny certified.
- Made in the USAFormulated in the United States.
What customers reported after 60 days
- said their skin feels rejuvenated
- 96%
- said it improved the look and feel of their skin
- 90%
- said it helped reduce the look of puffiness
- 93%
Based on customer study found that 92% saw brighter skin with AHA BHA PHA Dark Spot Cream, 93% experienced all-day hydration with Advanced BodyEssence, 97% noticed smoother skin with our Age-Defying Serum, and 90% of sensitive skin users had no irritation with Mesoderm RX products.
Before
After
Before
After
Before
After
Before
After4.9 out of 5, from 1,236 customers
In their own words, after making us part of their routine.
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Gentle yet effective!
“Great product! I’ve used different AHA BHA PHA Dark Spot serums in the past that have caused irritation to my skin BUT this formula is great! It is effective without causing issues to my sensitive skin.”
Hayleigh T.AHA + BHA + PHA Skin Brightening Serum 30ml -
Using it for years
“Love the serum! I’ve been using them for years!”
Karen F.AHA + BHA + PHA Skin Brightening Serum 30ml -
Amazing product
“I bought a few items and I love them all in conjunction with each other.”
Staci B.Pigment Restraint Cream -
The best of the best
“This is the best Intimate Whitening Cream, zero irritation I’m really enjoying the results, my skin is glowing and I love it!”
Faith F.Intimate Skin Brightening Cream for Under Arms, Inner Thighs & Private Area
Try it for 60 days
If it is not right for you, return unused, unopened items within 60 days of delivery for a refund. Read the policy
- Money-Back Guarantee
- Easy Returns
- Born in California, made in the USA
- 60-day happiness guarantee
- Cruelty-free, Leaping Bunny certified
- Clinically-studied active ingredients
Which product is right for me?
Start with your main concern: the AHA + BHA + PHA Serum for dark spots and dullness. Pigment Restraint Cream for stubborn spots. The Intimate Brightening Cream for underarms and the bikini line. And Pigment Restraint Anti SunSpot SPF 50+ every morning. Not sure? Ask us.
Are your products suitable for sensitive skin?
Our formulas are fragrance free, dye free, paraben free and sulfate free. Any brightening active can tingle at first, so patch test and introduce one new product at a time.
How long until I see a difference?
Skin renews gradually, so give any brightening routine consistent daily use over several weeks before judging results. Individual results vary.
How fast is shipping?
Orders ship within 1 to 2 business days. Standard US shipping takes 3 to 5 business days and is free on orders over $59.
What if it is not right for me?
Unused, unopened items can be returned within 60 days of delivery under our money-back guarantee. If an item arrives damaged or incorrect, contact us within 7 days and we will replace or refund it. Read the full policy.
How do subscriptions work?
Choose Subscribe & Save on every delivery. There is no commitment: skip, reschedule or cancel anytime from your account.
Daily sun protection
Pigment Restraint Ultra High Sun Protection
Shields skin from the UV damage that leads to dark spots.
- Protects against environmental stressors
- Helps even out the look of skin tone
- Supports healthy-looking radiance
Two decades of trusted skincare
For over two decades, mesoderm RX has made effective skincare you can trust. Our cruelty-free formulas leave out hydroquinone, parabens, mineral oil, petrolatum, sulfates and phthalates.
- Two decades in skincare
- Science-led formulas
- Hydroquinone-free
60-Day Money-Back Guarantee
Feel the difference with every application
Unlock your best skin yet
Collagen Revitalizer hydrates, brightens and renews for a glow you will love.
- High-potency formulaMade with actives chosen for visible results.
- Lightweight, fast-absorbingA cream that sinks in without a greasy feel.
- Formulated in the USACarefully Selected Quality Ingredients